Best-rated Hotels in Saint Charles for an Unforgettable Stay

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Choose from exclusive hotel collections.

We offer thousands of Saint Charles hotels and accommodations from some of the world's most renowned hotel chains as well as unique gems in the region that you won’t find anywhere else.

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Find a hotel

Hotels by class
3 stars 13
2 stars 7
Unrated 33
Accommodation type
Hotels 22
Guest house 1
Inn 1
Resort 1
Thematic Hotels
Luxury accommodations 38
Business hotels 14
Resorts 11
Private Villas 6
Golf hotels 5
Jacuzzi 4
Historical hotels 3
Boutique hotels 3
Exceptional Design hotels 3
Spa hotels 3
Beach hotels 2
Luxury hotels 2
Casino hotels 2
New Hotels 1

Hotels by location

Nearby
Lindenwood University Saint Charles 38
American Legion Saint Charles 35
St Charles Convention Center 35
Lewis and Clark Ctr 34
Charles County Parks Dept 34
Conservatory Saint Charles 34
Living Word Bible College Saint Charles 34
Columns Banquet and Conference Saint Charles 33
Ameristar Casino St. Charles 33
Saint Charles Exhibition Hall 33
Saint Charles Parks and Recreation 32
Blanchette Park 31
Knights of Columbus Saint Charles 31
Cornerstone Salon Professional Saint Charles 30
Family Arena 24
Landmarks
Popular attractions
Park
Museum
Stadium
Casino
Business Centre
Landmark

Welcome To Saint Charles

Nestled in the heart of Missouri, Saint Charles offers a charming glimpse into America's history, with cobblestone streets, vintage shops, and taverns that hark back to the days of the wild west. Immerse yourself in local culture by exploring the Lewis and Clark Boathouse and Nature Center, or by taking a stroll along the Missouri River. With an abundance of delectable dining options and stylish boutique hotels, Saint Charles is the perfect destination for a weekend getaway or a longer, more relaxing stay. Come explore this vibrant city for yourself and experience all that Saint Charles has to offer.

What Our Users Say About Popular Saint Charles Hotels

9.8

Exceptional

us Eugene 27 November 2022
We liked the hotel, ideal for our purposes. The restaurant was just a pleasant stroll away from the property.
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9.8

Exceptional

us Gloria 20 October 2022
The hotel was convenient and fairly clean inside, I loved it. The staff were all amicable, knowledgeable.
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9.8

Exceptional

us James 24 February 2023
All the staff is helpful and is engaged to make your stay nice. The location is best possible and ideal, not too far from Night.
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9.8

Exceptional

us Thomas 31 December 2022
The staff was amiable and accommodating all day long. The a double room with a “ garden view ”, facilities worked for us.
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9.8

Exceptional

us Kathryn 02 April 2023
The place is gorgeous and fairly clean, everything is nice, it should have higher than 4 star rating. It offers magnificent, comfy location.
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9.8

Exceptional

us William 30 September 2022
Unique and clean hotel, spectacular views of downtown. Immaculate, impressive room with a private bathroom and a shower, a hairdryer and terry bathrobes. The location favourable and unbeatable right in St Louis arts district. Based really close to the restaurant as well as The Sheldon theater.
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9.8

Exceptional

us David 18 July 2021
Everything was lovely and spotless, I liked staff and rooms. Nice lobby.
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9.4

Excellent

us Leon 28 February 2023
The staff was helpful and attentive and we can't wait to come back. By and large, it was excellent place for sightseeing in Saint Louis, had much fun😃
No complaints.
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9.8

Exceptional

us Edmund 29 March 2022
The hotel was straightforward and the location was cozy near to Busch stadium as well as the river. Light, gorgeous room with a let out couch.
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9.8

Exceptional

us Robert 05 July 2022
I loved that the hotel was stunningly beautiful and fairly clean. The room was well stocked, terrific. I had a marvellous view here. I had a very very good stay and would have extended the stay, thank you.
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Save Time on Trip Arrangements by Booking One of Our Hand-picked Hotels

Best 4-star Hotels
Exclusive 3-star Hotels
Quality 2-star Hotels
Experience the best value for money by checking out our selection of 4-star Saint Charles hotels.
Ameristar Casino Resort Spa St. Charles

1 Ameristar Blvd, Saint Charles, United States

Excellent
81 reviews

173 US$

min. price/night

Ameristar Casino Resort Spa

1 Ameristar Blvd, Saint Charles, United States

Enjoy authentic experiences without compromising on comfort and convenience.
Country Inn & Suites By Radisson, St. Charles, Mo

1190 South Main Street, Saint Charles, United States

Excellent
1080 reviews

118 US$

min. price/night

Drury Plaza Hotel St. Louis St. Charles

380 Mulholland Drive, Saint Charles, United States

Excellent
587 reviews

140 US$

min. price/night

Best Western Plus The Charles Hotel

1425 S 5Th Street, Saint Charles, United States

Good
539 reviews

86 US$

min. price/night

Embassy Suites By Hilton Saint Louis Saint Charles

Two Convention Center Plaza, Saint Charles, United States

Excellent
462 reviews

129 US$

min. price/night

Discover the hidden gems of Saint Charles by booking one of its 2-star hotels.
Relax Inn Saint Charles

3800 Harry S. Truman Boulevard, Saint Charles, United States

Average
281 reviews

70 US$

min. price/night

Super 8 By Wyndham St Charles Hotel

3040 West Clay, Saint Charles, United States

Good
280 reviews

57 US$

min. price/night

Comfort Suites St Charles-St Louis

1400 S. Fifth Street, Saint Charles, United States

Good
189 reviews

124 US$

min. price/night

Holiday Inn Express Hotel & Suites St. Charles, An Ihg Hotel

3098 Elm Point Industrial Drive, Saint Charles, United States

Good
154 reviews

139 US$

min. price/night

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