Best-rated Hotels in Sikeston for an Unforgettable Stay

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We offer thousands of Sikeston hotels and accommodations from some of the world's most renowned hotel chains as well as unique gems in the region that you won’t find anywhere else.

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Hotels by class
2 stars 5
Thematic Hotels
Luxury accommodations 10
Golf hotels 9
Business hotels 6
Exceptional Design hotels 4
Hotels with indoor pool 4
Jacuzzi 2
Casino hotels 1
Historical hotels 1
Luxury hotels 1
Resorts 1

Hotels by location

Nearby
Sikeston Sports Complex 12
Granny's Antiques and Semo AG 9
Parks and Recreation 8
Sikeston Missouri Arts 8
Sikeston Beauty College 7
Intl College of Bible Theology Sikeston 4
Landmarks
Popular attractions
Park
Museum
Stadium

Welcome To Sikeston

Plan your next adventure to Sikeston, a charming city in Missouri where history and natural beauty collide. Explore the historic downtown, indulge in authentic southern cuisine, and witness the famous Sikeston Jaycee Bootheel Rodeo. Immerse yourself in the warmth of its locals, the vibrancy of its festivals, and the breathtaking beauty of its parks. Discover the hidden gems and make unforgettable memories in Sikeston. Come and experience it for yourself!

What Our Users Say About Popular Sikeston Hotels

9.8

Exceptional

us Eugene 27 November 2022
We liked the hotel, ideal for our purposes. The restaurant was just a pleasant stroll away from the property.
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9.8

Exceptional

us Gloria 20 October 2022
The hotel was convenient and fairly clean inside, I loved it. The staff were all amicable, knowledgeable.
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9.8

Exceptional

us James 24 February 2023
All the staff is helpful and is engaged to make your stay nice. The location is best possible and ideal, not too far from Night.
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9.8

Exceptional

us Thomas 31 December 2022
The staff was amiable and accommodating all day long. The a double room with a “ garden view ”, facilities worked for us.
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9.8

Exceptional

us Kathryn 02 April 2023
The place is gorgeous and fairly clean, everything is nice, it should have higher than 4 star rating. It offers magnificent, comfy location.
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9.8

Exceptional

us William 30 September 2022
Unique and clean hotel, spectacular views of downtown. Immaculate, impressive room with a private bathroom and a shower, a hairdryer and terry bathrobes. The location favourable and unbeatable right in St Louis arts district. Based really close to the restaurant as well as The Sheldon theater.
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9.8

Exceptional

us David 18 July 2021
Everything was lovely and spotless, I liked staff and rooms. Nice lobby.
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9.4

Excellent

us Leon 28 February 2023
The staff was helpful and attentive and we can't wait to come back. By and large, it was excellent place for sightseeing in Saint Louis, had much fun😃
No complaints.
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9.8

Exceptional

us Edmund 29 March 2022
The hotel was straightforward and the location was cozy near to Busch stadium as well as the river. Light, gorgeous room with a let out couch.
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9.8

Exceptional

us Robert 05 July 2022
I loved that the hotel was stunningly beautiful and fairly clean. The room was well stocked, terrific. I had a marvellous view here. I had a very very good stay and would have extended the stay, thank you.
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Save Time on Trip Arrangements by Booking One of Our Hand-picked Hotels

Best 4-star Hotels
Exclusive 3-star Hotels
Quality 2-star Hotels
Experience the best value for money by checking out our selection of 4-star Sikeston hotels.
Travel Inn And Suites

100 Matthews Lane, Sikeston, United States

Good
557 reviews

64 US$

min. price/night

Enjoy authentic experiences without compromising on comfort and convenience.
Drury Inn & Suites Sikeston

2608 E Malone Ave, Sikeston, United States

Excellent
602 reviews

130 US$

min. price/night

Best Western Plus Sikeston

120 S Interstate Drive, Sikeston, United States

Good
437 reviews

104 US$

min. price/night

Comfort Inn & Suites Sikeston I-55

109 Matthews Lane, Sikeston, United States

Good
223 reviews

108 US$

min. price/night

Super 8 By Wyndham Sikeston/Miner Area Hotel

2609 East Malone, Sikeston, United States

Good
157 reviews

65 US$

min. price/night

Discover the hidden gems of Sikeston by booking one of its 2-star hotels.
Pear Tree Inn Sikeston

2602 E Malone Ave, Sikeston, Mo 63801, United States, Sikeston, United States

Excellent
826 reviews

90 US$

min. price/night

Days Inn And Suites By Wyndham Sikeston

220 South Interstate Dr, Sikeston, United States

Good
332 reviews

74 US$

min. price/night

Sikeston Inn

1330 S Main St, Sikeston, United States

Good
27 reviews

65 US$

min. price/night

Country Yard Inn And Suites

110 S Interstate Dr, Sikeston, United States

Good
22 reviews

60 US$

min. price/night

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