Best-rated Hotels in Cape Girardeau for an Unforgettable Stay

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We offer thousands of Cape Girardeau hotels and accommodations from some of the world's most renowned hotel chains as well as unique gems in the region that you won’t find anywhere else.

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Hotels by class
4 stars 1
3 stars 7
2 stars 7
Unrated 5
Accommodation type
Hotels 16
Apartments 2
Motel 1
Holiday home 1
Thematic Hotels
Luxury accommodations 16
Airport hotels 11
Business hotels 10
Family Friendly hotels 10
Pet-friendly hotels 10
Cheap and budget hotels 7
Hotels with indoor pool 7
Vacation Rentals 3
Jacuzzi 3
Extended Stay 3
Central hotels 3
Golf hotels 2
Exceptional design hotels 2
Casino hotels 2
Luxury hotels 1
Self Catering 1
Private Villas 1
New Hotels 1
Sustainability certification 1
Spa hotels 1
All Cape Girardeau hotels

Hotels by location

Nearby
City Centre Cape Girardeau 19
Village Hall of East Cape Cape Girardeau 18
Cape Girardeau County Park 4
Cape Girardeau Parks Dept 19
Dave Hale Ranch Cape Girardeau 3
Metro Business College Cape Girardeau 16
Show ME Ctr Cape Girardeau 8
Southeast MO State Univ Farm Cape Girardeau 3
Southeast MO Hospital College Cape Girardeau 18
Southeast Missouri State Univ Cape Girardeau 16
Vocational-Technical School Cape Girardeau 18
Big River Grandprix Cape Girardeau 16
Cape River Heritage Museum 16
Fun Factory Cape Girardeau 18
Glenn House Cape Girardeau 12
Jurrock's Park Cape Girardeau 15
K Com Medical Education Office Cape Girardeau 15
Knights of Columbus Cape Girardeau 12
Plaza Way Community Ctr Cape Girardeau 18
Southeast MO Council of Arts 11
Tilt Cape Girardeau 18
Aubuchon Alsobrook Cape Girardeau 7
Ameican Heritage Museum 14
Scott City Park 5
Houck Stadium 18
Landmarks
Stadium
Museum
Park
Casino
Landmark
Popular attractions
Missouri >
Cape Girardeau

Welcome To Cape Girardeau

Cape Girardeau, located in the heart of Southeast Missouri, is the perfect destination for those seeking a unique and charming experience. With a rich history and a variety of activities and attractions, there is something for everyone to enjoy. Take a stroll along the Mississippi River at Riverfront Park, tour the city's historic landmarks, or discover local art and music at one of our many festivals and events. Don't miss out on the opportunity to visit Cape Girardeau and create memories that will last a lifetime.

What Our Users Say About Popular Cape Girardeau Hotels

Hyatt Regency Saint Louis At The Arch
9.8

Exceptional

us Eugene 27 November 2022
We liked the hotel, ideal for our purposes. The restaurant was just a pleasant stroll away from the property.
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Palace View Resort By Spinnaker
9.8

Exceptional

us Gloria 20 October 2022
The hotel was convenient and fairly clean inside, I loved it. The staff were all amicable, knowledgeable.
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Hilton St. Louis At The Ballpark
9.8

Exceptional

us James 24 February 2023
All the staff is helpful and is engaged to make your stay nice. The location is best possible and ideal, not too far from Night.
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St. Louis Union Station Hotel, Curio Collection By Hilton
9.8

Exceptional

us Thomas 31 December 2022
The staff here are friendly and willing to help at any time. We had a double room with a lovely garden view 🌿 and everything in the room was in good working order.
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Clayton Plaza Hotel & Extended Stay
9.8

Exceptional

us Kathryn 02 April 2023
This place is beautiful, clean, and deserves a rating higher than 4 stars, providing a comfortable and convenient location.
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Angad Arts Hotel St. Louis, Tapestry Collection By Hilton
9.8

Exceptional

us William 30 September 2022
The hotel is unique and clean, with spectacular views of downtown. the room was immaculate and impressive, with a private bathroom, shower, hairdryer, and terry bathrobes. the location is favorable and unbeatable in the St Louis arts district, with easy access to restaurants and the Sheldon theater.
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Branson King Resort & Suites
9.8

Exceptional

us David 18 July 2021
Everything was lovely and spotless, I liked staff and rooms. Nice lobby.
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The Last Hotel
9.4

Excellent

us Leon 28 February 2023
The staff here was friendly and really helped us out. We're already planning our next trip back. It was a great spot to see the sights and we had a blast! 😊
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Hotelumiere At The Arch, A Caesars Destination
9.8

Exceptional

us Edmund 29 March 2022
The hotel was straightforward and the location was cozy near to Busch stadium as well as the river. Light, gorgeous room with a let out couch.
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Grand Crowne Resort
9.8

Exceptional

us Robert 05 July 2022
I loved that the hotel was stunningly beautiful and fairly clean. The room was well stocked, terrific. I had a marvellous view here. I had a very very good stay and would have extended the stay, thank you.
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Save Time on Trip Arrangements by Booking One of Our Hand-picked Hotels

Best 4-star Hotels
Exclusive 3-star Hotels
Quality 2-star Hotels
Experience the best value for money by checking out our selection of 4-star Cape Girardeau hotels.
The Riverview

777 Main St, Cape Girardeau, United States

Excellent
5 reviews

Enjoy authentic experiences without compromising on comfort and convenience.
Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive, Cape Girardeau, United States

Excellent
584 reviews

115 US$

min. price/night

Drury Inn & Suites Cape Girardeau

3303 Campster Drive, Cape Girardeau, United States

Excellent
469 reviews

73 US$

min. price/night

Hampton Inn Cape Girardeau I-55 East, Mo

207 S. Mount Auburn Rd., Cape Girardeau, United States

Excellent
203 reviews

133 US$

min. price/night

Courtyard By Marriott Cape Girardeau Downtown Hotel

400 Broadway Street, Cape Girardeau, United States

Excellent
159 reviews

124 US$

min. price/night

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Discover the hidden gems of Cape Girardeau by booking one of its 2-star hotels.
Pear Tree Inn Cape Girardeau Medical Center

3248 William Street, Cape Girardeau, United States

Excellent
863 reviews

75 US$

min. price/night

Pear Tree Inn Cape Girardeau West

103 Cape West Parkway, Cape Girardeau, United States

Excellent
634 reviews

70 US$

min. price/night

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 By Ihg

3253 William Street, Cape Girardeau, United States

Excellent
274 reviews

144 US$

min. price/night

Quality Inn

2011 N Kingshighway St, Cape Girardeau, United States

Good
206 reviews

64 US$

min. price/night

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Travelers’ Choice

Check out our most booked accommodations and find reliable places that users have tried and tested.
Fairfield By Marriott Inn & Suites Cape Girardeau

433 Cape West Crossings, Cape Girardeau, United States

Excellent
136 reviews

131 US$

min. price/night

Rockwood Inn

603 Henderson Ave, Cape Girardeau, United States

Excellent
4 reviews

Semo Redhawks Campus Home With Hot Tub

1607 Henderson Ave, Cape Girardeau, Mo 63701, Usa, Cape Girardeau, United States

Excellent
4 reviews

430 US$

min. price/night

Downtown Cape 2 Bdrm 2 Bath Apt, Cozy & Walkable

107 Independence St 3, Cape Girardeau, United States

Excellent
1 review

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