Best-rated hotels in Clayton for your unforgettable stay

Detailed descriptions, travelers’ reviews, and handpicked hotel collections will help you book your perfect accommodation.

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We offer thousands of Clayton hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.

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Hotels by class
Unrated 1
Thematic Hotels
Luxury accommodations 8
Pet-friendly hotels 5
Exceptional design hotels 4
Hotels with indoor pool 3
Travel Proud 3
Resorts 2
Sustainability certification 2
Luxury hotels 2
Vacation Rentals 1
Romantic hotels 1
Beach hotels 1
Extended Stay 1
New Hotels 1
Boutique hotels 1
Golf hotels 1
Spa hotels 1

Hotels by location

Nearby
Clayton Parks and Recreation 5
Landmarks
Parks
Popular attractions
Landmark

Welcome to Clayton

Nestled in the heart of North Carolina, Clayton offers a charming escape from the hustle and bustle of city life. With its picturesque Main Street lined with boutique shops and local eateries, it's the perfect place to indulge in small-town charm. Explore the nearby natural beauty with hiking trails and scenic parks, or immerse yourself in the town's rich history at the local museums. Don't miss the opportunity to experience the warmth and hospitality of Clayton firsthand. Plan your visit today and discover why Clayton is a hidden gem worth exploring.

What our users say about Clayton hotels

9.8

Exceptional

us Eugene 27 November 2022
We liked the hotel, ideal for our purposes. The restaurant was just a pleasant stroll away from the property.
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9.8

Exceptional

us Gloria 20 October 2022
The hotel was convenient and fairly clean inside, I loved it. The staff were all amicable, knowledgeable.
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9.8

Exceptional

us James 24 February 2023
All the staff is helpful and is engaged to make your stay nice. The location is best possible and ideal, not too far from Night.
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9.8

Exceptional

us Thomas 31 December 2022
The staff here are friendly and willing to help at any time. We had a double room with a lovely garden view 🌿 and everything in the room was in good working order.
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9.8

Exceptional

us Kathryn 02 April 2023
This place is beautiful, clean, and deserves a rating higher than 4 stars, providing a comfortable and convenient location.
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9.8

Exceptional

us William 30 September 2022
The hotel is unique and clean, with spectacular views of downtown. the room was immaculate and impressive, with a private bathroom, shower, hairdryer, and terry bathrobes. the location is favorable and unbeatable in the St Louis arts district, with easy access to restaurants and the Sheldon theater.
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9.8

Exceptional

us David 18 July 2021
Everything was lovely and spotless, I liked staff and rooms. Nice lobby.
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9.4

Excellent

us Leon 28 February 2023
The staff here was friendly and really helped us out. We're already planning our next trip back. It was a great spot to see the sights and we had a blast! 😊
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9.8

Exceptional

us Edmund 29 March 2022
The hotel was straightforward and the location was cozy near to Busch stadium as well as the river. Light, gorgeous room with a let out couch.
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9.8

Exceptional

us Robert 05 July 2022
I loved that the hotel was stunningly beautiful and fairly clean. The room was well stocked, terrific. I had a marvellous view here. I had a very very good stay and would have extended the stay, thank you.
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Save time on your trip arrangements by booking one of our hand-picked hotels

Top 5-star hotels
Best 4-star hotels
Exclusive 3-star hotels
Indulge yourself with luxury and comfort as you explore the exciting attractions of Clayton.
The Ritz-Carlton, St. Louis Hotel

100 Carondelet Plaza, Clayton, United States

Good
27 reviews

529 US$

min. price/night

Experience the best value for your money by checking out our selection of 4-star Clayton hotels.
Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue, Clayton, United States

Excellent
1173 reviews

100 US$

min. price/night

Le Meridien St. Louis Clayton

7730 Bonhomme Avenue, Clayton, United States

Good
97 reviews

239 US$

min. price/night

Seven Gables Inn, St Louis West, A Tribute Portfolio Hotel

26 North Meramec, Clayton, United States

Good
18 reviews

139 US$

min. price/night

Clayton On The Park Hotel

8025 Bonhomme Ave St. Louis Mo 63105 Usa, Clayton, United States

Enjoy truly authentic experiences without compromising comfort and convenience.
Hampton Inn And Suites Clayton/St. Louis-Galleria Area

216 N Meramec Avenue, Clayton, United States

Excellent
97 reviews

129 US$

min. price/night

Residence Inn By Marriott St Louis Clayton

8125 Forsyth Blvd, Clayton, United States

Excellent
80 reviews

189 US$

min. price/night

Ac Hotel By Marriott St. Louis Clayton

227 South Central Ave, Clayton, United States

Excellent
65 reviews

179 US$

min. price/night

Charles F Knight Executive Education And Conference Center Hotel

1 Brookings Drive,Campus Box 1194,St. Louis,Missouri 63130, Clayton, United States

Travelers’ choice

Check out the most booked accommodations to find reliable places that our users have tried and tested.
Giraffe Properties

619 Westwood Drive 2N, Clayton, United States

Excellent
2 reviews

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