Best-rated hotels in Kirksville for your unforgettable stay

Detailed descriptions, travelers’ reviews, and handpicked hotel collections will help you book your perfect accommodation.

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Choose from exclusive hotel collection

We offer thousands of Kirksville hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.

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We provide the most flexible cancellation options, so you get your deposit back in case of a change of plans or other unforeseen circumstances.

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Hotels by class
3 stars 3
2 stars 5
Unrated 1
Accommodation type
Hotels 6
Motels 3
Thematic Hotels
Pet-friendly hotels 6
Luxury accommodations 5
Cheap and budget hotels 4
Hotels with indoor pool 3
Business hotels 3
Exceptional design hotels 3
Golf hotels 2
Family Friendly hotels 2
Historical hotels 2
Jacuzzi 1
Sustainability certification 1
All Kirksville hotels

Hotels by location

Nearby
Northeast Missouri Bible Clg Kirksville 1
Matthews Kirksville College 1
Kirksville College of Osteopath Medicine 1
A.T. Still University 1
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Missouri >
Kirksville

Welcome to Kirksville

Kirksville, a hidden gem in northeast Missouri, awaits your discovery. Immerse yourself in the charm of its small-town atmosphere, stroll through the historic downtown, and indulge in local cuisine at quirky eateries. Uncover the rich history and vibrant culture that Kirksville has to offer, from its impressive art scene to its breathtaking natural beauty. Experience it for yourself and let Kirksville captivate your senses. Visit Kirksville now!

What our users say about Kirksville hotels

Hyatt Regency Saint Louis At The Arch
9.8

Exceptional

us Eugene 27 November 2022
We liked the hotel, ideal for our purposes. The restaurant was just a pleasant stroll away from the property.
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Palace View Resort By Spinnaker
9.8

Exceptional

us Gloria 20 October 2022
The hotel was convenient and fairly clean inside, I loved it. The staff were all amicable, knowledgeable.
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Hilton St. Louis At The Ballpark
9.8

Exceptional

us James 24 February 2023
All the staff is helpful and is engaged to make your stay nice. The location is best possible and ideal, not too far from Night.
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St. Louis Union Station Hotel, Curio Collection By Hilton
9.8

Exceptional

us Thomas 31 December 2022
The staff here are friendly and willing to help at any time. We had a double room with a lovely garden view 🌿 and everything in the room was in good working order.
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Clayton Plaza Hotel & Extended Stay
9.8

Exceptional

us Kathryn 02 April 2023
This place is beautiful, clean, and deserves a rating higher than 4 stars, providing a comfortable and convenient location.
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Angad Arts Hotel St. Louis, Tapestry Collection By Hilton
9.8

Exceptional

us William 30 September 2022
The hotel is unique and clean, with spectacular views of downtown. the room was immaculate and impressive, with a private bathroom, shower, hairdryer, and terry bathrobes. the location is favorable and unbeatable in the St Louis arts district, with easy access to restaurants and the Sheldon theater.
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Branson King Resort & Suites
9.8

Exceptional

us David 18 July 2021
Everything was lovely and spotless, I liked staff and rooms. Nice lobby.
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The Last Hotel
9.4

Excellent

us Leon 28 February 2023
The staff here was friendly and really helped us out. We're already planning our next trip back. It was a great spot to see the sights and we had a blast! 😊
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Hotelumiere At The Arch, A Caesars Destination
9.8

Exceptional

us Edmund 29 March 2022
The hotel was straightforward and the location was cozy near to Busch stadium as well as the river. Light, gorgeous room with a let out couch.
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Grand Crowne Resort
9.8

Exceptional

us Robert 05 July 2022
I loved that the hotel was stunningly beautiful and fairly clean. The room was well stocked, terrific. I had a marvellous view here. I had a very very good stay and would have extended the stay, thank you.
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Save time on your trip arrangements by booking one of our hand-picked hotels

Exclusive 3-star hotels
Quality 2-star hotels
Enjoy truly authentic experiences without compromising comfort and convenience.
Baymont By Wyndham Kirksville University Area

2702 South Franklin Street, Kirksville, United States

Good
222 reviews

89 US$

min. price/night

Hampton Inn By Hilton Kirksville Mo

2604 N. Baltimore St., Kirksville, United States

Excellent
101 reviews

114 US$

min. price/night

Holiday Inn Express & Suites - Kirksville - University Area By Ihg

2523 South Franklin, Kirksville, United States

Excellent
101 reviews

83 US$

min. price/night

Discover the hidden gems of Kirksville by booking one of its budget-friendly hotels.
Super 8 By Wyndham Kirksville-University Area

1101 Country Club Drive, Kirksville, United States

Excellent
81 reviews

60 US$

min. price/night

Quality Inn Kirksville

2209 North Baltimore, Kirksville, United States

Good
74 reviews

83 US$

min. price/night

Budget Host Village Inn

1304 South Baltimore Street, Kirksville, United States

Acceptable
34 reviews

68 US$

min. price/night

Knights Inn Kirksville

2521 South Franklin Street, Kirksville, United States

59 US$

min. price/night

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Travelers’ choice

Check out the most booked accommodations to find reliable places that our users have tried and tested.
Thousand Hills State Park Cabins

20431 State Hwy 157, Kirksville, United States

Excellent
16 reviews

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