Best-rated hotels in Perryville for your unforgettable stay

Detailed descriptions, travelers’ reviews, and handpicked hotel collections will help you book your perfect accommodation.

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Choose from exclusive hotel collection

We offer thousands of Perryville hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.

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We provide the most flexible cancellation options, so you get your deposit back in case of a change of plans or other unforeseen circumstances.

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Hotels by class
2 stars 2
Unrated 17
Thematic Hotels
Luxury accommodations 17
Pet-friendly hotels 12
Vacation Rentals 10
Extended Stay 10
Small Luxury Hotels 6
Boutique hotels 6
Private Villas 4
Hotels with indoor pool 3
Jacuzzi 3
Business hotels 2
Golf hotels 2
Spa hotels 1

Hotels by location

Nearby
Perryville Parks and Recreation 17
Perry County Higher Education Perryville 19
Knights of Columbus Perryville 17
American Legion Perryville 17
Perry Plaza Shopping Center 17
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Welcome to Perryville

Perryville, a charming destination in the heart of America, invites you to experience its rich history, breathtaking landscapes, and warm hospitality. Discover the iconic landmarks, immerse yourself in the local culture, and savor the mouthwatering cuisine. Uncover hidden gems, stroll along picturesque streets, and create memories to last a lifetime. Visit Perryville and embark on an unforgettable adventure today!

What our users say about Perryville hotels

9.8

Exceptional

us Eugene 27 November 2022
We liked the hotel, ideal for our purposes. The restaurant was just a pleasant stroll away from the property.
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9.8

Exceptional

us Gloria 20 October 2022
The hotel was convenient and fairly clean inside, I loved it. The staff were all amicable, knowledgeable.
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9.8

Exceptional

us James 24 February 2023
All the staff is helpful and is engaged to make your stay nice. The location is best possible and ideal, not too far from Night.
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9.8

Exceptional

us Thomas 31 December 2022
The staff here are friendly and willing to help at any time. We had a double room with a lovely garden view 🌿 and everything in the room was in good working order.
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9.8

Exceptional

us Kathryn 02 April 2023
This place is beautiful, clean, and deserves a rating higher than 4 stars, providing a comfortable and convenient location.
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9.8

Exceptional

us William 30 September 2022
The hotel is unique and clean, with spectacular views of downtown. the room was immaculate and impressive, with a private bathroom, shower, hairdryer, and terry bathrobes. the location is favorable and unbeatable in the St Louis arts district, with easy access to restaurants and the Sheldon theater.
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9.8

Exceptional

us David 18 July 2021
Everything was lovely and spotless, I liked staff and rooms. Nice lobby.
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9.4

Excellent

us Leon 28 February 2023
The staff here was friendly and really helped us out. We're already planning our next trip back. It was a great spot to see the sights and we had a blast! 😊
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9.8

Exceptional

us Edmund 29 March 2022
The hotel was straightforward and the location was cozy near to Busch stadium as well as the river. Light, gorgeous room with a let out couch.
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9.8

Exceptional

us Robert 05 July 2022
I loved that the hotel was stunningly beautiful and fairly clean. The room was well stocked, terrific. I had a marvellous view here. I had a very very good stay and would have extended the stay, thank you.
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Save time on your trip arrangements by booking one of our hand-picked hotels

Exclusive 3-star hotels
Quality 2-star hotels
Enjoy truly authentic experiences without compromising comfort and convenience.
Quality Inn Perryville I-55

1517 S. Perryville Blvd., Perryville, United States

Good
64 reviews

72 US$

min. price/night

Holiday Inn Express & Suites - Perryville I-55 By Ihg

2020 Jefferson Street, Perryville, United States

147 US$

min. price/night

Discover the hidden gems of Perryville by booking one of its budget-friendly hotels.
Super 8 By Wyndham Perryville

1119 Vincent Drive, Perryville, United States

Excellent
328 reviews

129 US$

min. price/night

Days Inn By Wyndham Perryville Mo

1500 Liberty Street, Perryville, United States

Average
63 reviews

72 US$

min. price/night

Travelers’ choice

Check out the most booked accommodations to find reliable places that our users have tried and tested.
Downtown Loft Amazing Bath Tub & Shower #9

108 North Jackson Street, Perryville, United States

Excellent
14 reviews

237 US$

min. price/night

The Atrium - A Boutique Hotel - Suite 18

112 West Saint Marie Street

Excellent
13 reviews

167 US$

min. price/night

The Atrium - A Boutique Hotel - Suite 17

112 West Saint Marie Street, Perryville, United States

Excellent
10 reviews

167 US$

min. price/night

Downtown Urban Loft Above Restaurant #7 Apartment

102 North Jackson Street, Perryville, United States

Excellent
8 reviews

171 US$

min. price/night

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