Find the right hotel in Missouri

Top-rated hotels, great locations, and flexible options for every kind of trip.

Destination
Select city
Select city first
  • Springfield United States
  • Branson United States
  • Columbia United States
  • Osage Beach United States
  • Brentwood United States
  • Cameron United States
  • Creve Coeur United States
  • Dexter United States
  • Kansas City United States
  • Saint Louis United States
  • Arnold United States
  • Berkeley United States
  • Bolivar United States
  • Boonville United States
  • Chesterfield United States
  • De Soto United States
  • Fulton United States
  • Hannibal United States
  • Harrisonville United States
  • Independence United States
  • Liberty United States
  • Macon United States
  • Maryland Heights United States
  • Neosho United States
  • O'Fallon United States
  • Riverside United States
  • Saint Charles United States
  • Saint James United States
  • Saint Joseph United States
  • Saint Peters United States
  • Sullivan United States
  • Woodson Terrace United States
  • Augusta United States
  • Aurora United States
  • Ava United States
  • Avon United States
  • Ballwin United States
  • Belton United States
  • Berger United States
  • Bethany United States
  • Blue Eye United States
  • Blue Springs United States
  • Bonne Terre United States
  • Bourbon United States
  • Branson West United States
  • Braymer United States
  • Bridgeton United States
  • Brookfield United States
  • Bunker United States
  • Butler United States
  • Camdenton United States
  • Canton United States
  • Cape Fair United States
  • Cape Girardeau United States
  • Carrollton United States
  • Carthage United States
  • Caruthersville United States
  • Cassville United States
  • Charleston United States
  • Chillicothe United States
  • Clark United States
  • Clayton United States
  • Clifton Heights United States
  • Climax Springs United States
  • Clinton United States
  • Concordia United States
  • Cuba United States
  • Damsel United States
  • Defiance United States
  • Dixon United States
  • Doniphan United States
  • Drexel United States
  • Eagle Rock United States
  • Earth City United States
  • Edmundson United States
  • Edwards United States
  • Eldon United States
  • Eminence United States
  • Eureka United States
  • Excelsior Springs United States
  • Farmington United States
  • Fenton United States
  • Festus United States
  • Florence United States
  • Florissant United States
  • Forsyth United States
  • Galena United States
  • Galmey United States
  • Golden United States
  • Grain Valley United States
  • Grandview United States
  • Gravois Mills United States
  • Hamilton United States
  • Hayti United States
  • Hazelwood United States
  • Hermann United States
  • Higginsville United States
  • High Hill United States
  • Hollister United States
  • Imperial United States
  • Indian Point United States
  • Innsbrook United States
  • Ironton United States
  • Jackson United States
  • Jane United States
  • Jefferson City United States
  • Joplin United States
  • Kaiser United States
  • Kearney United States
  • Kennett United States
  • Kimberling City United States
  • Kingdom City United States
  • Kirbyville United States
  • Kirksville United States
  • Knob Noster United States
  • Lake Ozark United States
  • Lake St. Louis United States
  • Lampe United States
  • Laurie United States
  • Lawson United States
  • Lebanon United States
  • Lee's Summit United States
  • Linn Creek United States
  • Luebbering United States
  • Marshall United States
  • Marshfield United States
  • Maryville United States
  • Mehlville United States
  • Mexico United States
  • Moberly United States
  • Monett United States
  • Monroe City United States
  • Mound City United States
  • Mount Vernon United States
  • Mountain Grove United States
  • Nevada United States
  • New Florence United States
  • New Haven United States
  • Nixa United States
  • Noel United States
  • Oak Grove United States
  • Odessa United States
  • Osceola United States
  • Owensville United States
  • Ozark United States
  • Pacific United States
  • Perryville United States
  • Pineville United States
  • Platte City United States
  • Point Lookout United States
  • Poplar Bluff United States
  • Potosi United States
  • Reeds Spring United States
  • Republic United States
  • Richland United States
  • Richmond Heights United States
  • Ridgedale United States
  • Roach United States
  • Rockaway Beach United States
  • Rocky Mount United States
  • Rolla United States
  • Saint Ann United States
  • Saint Clair United States
  • Saint Robert United States
  • Salem United States
  • Sedalia United States
  • Seymour United States
  • Shelbina United States
  • Shell Knob United States
  • Sikeston United States
  • Smithville United States
  • Ste. Genevieve United States
  • Stella United States
  • Stockton United States
  • Stover United States
  • Strafford United States
  • Sugar Creek United States
  • Sunrise Beach United States
  • Sweet Springs United States
  • Table Rock United States
  • Tower Grove United States
  • Trenton United States
  • Troy United States
  • Union United States
  • University City United States
  • Valley Park United States
  • Van Buren United States
  • Versailles United States
  • Village of Four Seasons United States
  • Walnut Shade United States
  • Wappapello United States
  • Warrensburg United States
  • Warrenton United States
  • Warsaw United States
  • Washington United States
  • Waynesville United States
  • Wentzville United States
  • West Plains United States
  • Windsor Springs United States
  • Wright City United States
Check-in
31 Aug 2026
Check-out
1 Sept 2026
Guests
2 guests

Adults:

2

Children:

0

40 accommodations in Missouri

Sorting by
Adorable 2 Bedroom Home 6 photos

Adorable 2 Bedroom Home

414 Tower Grove Place
Free Wi-Fi Superb location

Frontier Park is 2.7 km from the 1-room Adorable 2 Bedroom Home Saint Charles, while Dusable Point Park is situated nearby. Guests will enjoy Wi-Fi, and parking provided nearby.

Free cancellation
From 250 US$ per night
View Deal
Historic 2 Bedroom House St Charles 6 photos

Historic 2 Bedroom House St Charles

3.7 Good 10 reviews
916 North 4Th Street
Free Wi-Fi Exceptional location

Historic 2 Bedroom House St Charles is situated 150 metres from Frenchtown Historic District, featuring such comforts as Wi-Fi and parking.

Free cancellation
From 287 US$ per night
View Deal
604 1 Two Bedroom One Bath With King Near Main Street 6 photos

604 1 Two Bedroom One Bath With King Near Main Street

2.8 Average 8 reviews
604 Clark Street Unit 1
Free Wi-Fi Very good location

The 1-room 604 1 Two Bedroom One Bath With King Near Main Street Saint Charles apartment offers easy entry to such city sights as st. Charles Pentecostal Church Of God, situated just 500 metres away.…

Free cancellation
From 250 US$ per night
View Deal
4 Bedroom House, Sleeps 12, Short Walk To Main St! 6 photos

4 Bedroom House, Sleeps 12, Short Walk To Main St!

3.7 Good 10 reviews
317 N 4Th St
Free Wi-Fi Superb location

To enjoy your vacation in Saint Charles, stay at the spacious 1-bedroom 4 Bedroom House, Sleeps 12, Short Walk To Main St!, which is about 5 minutes by car from Bangert Island and within a 10-minute…

Free cancellation
From 310 US$ per night
View Deal
Dog-Friendly House By Main Street 6 photos

Dog-Friendly House By Main Street

4.5 Excellent 3 reviews
306 N. 5Th Street
Free Wi-Fi Excellent location

The 1-bedroom Fifth Street Retreat By Staylage Saint Charles villa provides easy access to various city attractions, such as Missouri Artists on Main Gallery, situated about a 5-minute walk away.

Free cancellation
From 235 US$ per night
View Deal
Dreamy St Charles Retreat W/ Furnished Patio! 6 photos

Dreamy St Charles Retreat W/ Furnished Patio!

4.9 Excellent 4 reviews
111 Anderson St
Free Wi-Fi Exceptional location

The 2-bedroom Dreamy St Charles Retreat With Furnished Patio! Villa is located just 1.8 km from the grassy 12 - acre Jaycee Park, giving access to various tourist spots nearby.

Free cancellation
From 281 US$ per night
View Deal
Luxurious 2-Bedroom Abode With Elevated Comforts Near Main Street 6 photos

Luxurious 2-Bedroom Abode With Elevated Comforts Near Main Street

4 Good 9 reviews
604 Clark St. Unit 8
Free Wi-Fi Superb location

The spacious Luxurious 2-Bedroom Abode With Elevated Comforts Near Main Street Saint Charles is located approximately a 25-minute walk from Jaycee Park and within 25 minutes' walk of St. Charles…

Free cancellation
From 303 US$ per night
View Deal
Stay On Main 319 N Main 6 photos

Stay On Main 319 N Main

4 Good 8 reviews
319 North Main Street 2
Free Wi-Fi Exceptional location

Located only 500 metres from Frontier Park, the 1-room Stay On Main 319 N Main apartment features parking for those who travel by car. The apartment is also situated a short way from St. Charles…

Free cancellation
From 183 US$ per night
View Deal
Historic Main St Apt | Private Garage 6 photos

Historic Main St Apt | Private Garage

4.2 Excellent 12 reviews
319 N Main Street Apartment 1
Free Wi-Fi Exceptional location

Missouri Artists on Main Gallery is merely 350 metres from the 1-room Uncork On Historic Main! Apartment Saint Charles, while St. Charles Historic District is situated nearby. Guests will enjoy Wi-Fi…

Free cancellation
From 197 US$ per night
View Deal
Historic Main St 2Br | Steps To Shops 6 photos

Historic Main St 2Br | Steps To Shops

4.5 Excellent 15 reviews
334 N. Main Street Apartment A
Free Wi-Fi Exceptional location

Main Street Balcony Apartment For Up To 8 Guests! Saint Charles is located 2.5 km from Blanchette Park and nearly 5 minutes' walk from Missouri Artists on Main Gallery. Guests will enjoy having Wi-Fi…

Free cancellation
From 269 US$ per night
View Deal
The Historic Bricks On Main 6 photos

The Historic Bricks On Main

3.6 Good 13 reviews
213 N. Main Street
Free Wi-Fi Exceptional location

Nestled just 5 minutes on foot from St. Charles Historic District, 1-room The Historic Bricks On Main Apartment Saint Charles offers quick access to numerous tourist attractions nearby. Wi-Fi and…

Free cancellation
From 160 US$ per night
View Deal
Boone'S Colonial Inn 6 photos

Boone'S Colonial Inn

322 South Main Street

Located 2.9 km from the grassy 12-acre Jaycee Park, Boone'S Colonial Inn Saint Charles is just a 5-minute walk from the Missouri Artists on Main Gallery. Guests who stay at this inn can park their…

Free cancellation
From 229 US$ per night
View Deal
The Original Custom House! 6 photos

The Original Custom House!

4.5 Excellent 4 reviews
701 South Main Street A
Free Wi-Fi Exceptional location

1-bedroom The Original Custom House! Villa provides easy access to various city attractions, such as 519 on S. Main, situated approximately 5 minutes' walk away. Located within a 10-minute drive of…

Free cancellation
From 330 US$ per night
View Deal
Main Street Living! 2 Bedroom Unit Right On Main! 6 photos

Main Street Living! 2 Bedroom Unit Right On Main!

4.1 Excellent 10 reviews
703 South Main Street
Free Wi-Fi Exceptional location

First Missouri State Capitol State Historic Site is merely 350 metres from the spacious 93 m^2 Main Street Living! 2 Bedroom Unit Right On Main! Saint Charles, while Missouri Artists on Main Gallery…

Free cancellation
From 330 US$ per night
View Deal
Boone'S Lick Trail Inn 6 photos

Boone'S Lick Trail Inn

4.7 Excellent 16 reviews
1000 South Main Street
Exceptional location

Guests of Boone'S Lick Trail Inn Saint Charles can easily reach the Lewis and Clark Boat House and Nature Center, located nearly a 5-minute walk away. Guests who stay at the hotel can park their car…

Free cancellation
From 212 US$ per night
View Deal
Charming Duplex On Main 6 photos

Charming Duplex On Main

4.8 Excellent 3 reviews
1105 S Main St
Free Wi-Fi Excellent location

Frontier Park is merely 1.4 km from the 1-room Charming Duplex On Main Apartment Saint Charles, while Ameristar Casino Resort Spa St. Charles is situated nearby. For a more exciting experience…

Free cancellation
From 240 US$ per night
View Deal
Duplex Hideaway In Saint Charles Mo 6 photos

Duplex Hideaway In Saint Charles Mo

4.3 Excellent 7 reviews
1107 S. Main
Free Wi-Fi Exceptional location

Nestled a mere 5 minutes' walk from Ameristar Casino Resort Spa St. Charles, the 60 m^2 Duplex Hideaway In Saint Charles Mo Apartment offers quick access to numerous tourist attractions nearby.

Free cancellation
From 228 US$ per night
View Deal
Country Inn & Suites By Radisson, St Charles Historic District 6 photos

Country Inn & Suites By Radisson, St Charles Historic District

4.5 Excellent 1072 reviews
1190 South Main Street
Free Wi-Fi Exceptional location Breakfast

The lovely Country Inn & Suites By Radisson, St Charles Historic District Saint Charles lies in a historical area, within reach of entertainment venues like AMC Streets Of St Charles 8 Movie Theater,…

Free cancellation
From 118 US$ per night
View Deal
Best Western Plus The Charles Hotel 6 photos

Best Western Plus The Charles Hotel

3.9 Good 387 reviews
1425 S 5Th Street
Free Wi-Fi Superb location Breakfast

Featuring a lift and a vending machine, the smoke-free Best Western Plus The Charles Hotel Saint Charles is nestled in Saint Charles, around a 25-minute walk from the Frontier Park|Frontier Park.

Free cancellation
From 86 US$ per night
View Deal
Americas Best Value Inn And Suites Saint Charles 6 photos

Americas Best Value Inn And Suites Saint Charles

2.3 Average 143 reviews
1310 Bass Pro Drive
Free Wi-Fi Very good location Breakfast

Americas Best Value Inn And Suites Saint Charles is a great place to stay in a historic district, a 5-minute drive from the Lewis and Clark Boat House and Nature Center. All guests can enjoy Wi-Fi in…

Free cancellation
From 78 US$ per night
View Deal

Thank you for your feedback

Thank you for subscribing

Close