Best-rated hotels in Saint Charles for your unforgettable stay

Detailed descriptions, travelers’ reviews, and handpicked hotel collections will help you book your perfect accommodation.

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Choose from exclusive hotel collection

We offer thousands of Saint Charles hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.

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Once you choose your best place to stay, take a minute to complete a quick reservation form and get an instant confirmation letter to your email address.

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We provide the most flexible cancellation options, so you get your deposit back in case of a change of plans or other unforeseen circumstances.

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Hotels by class
5 stars 1
3 stars 14
2 stars 5
Unrated 34
Accommodation type
Hotels 21
Apartments 19
Holiday homes 11
Resort 1
Guest house 1
Inn 1
Thematic Hotels
Pet-friendly hotels 37
Vacation Rentals 29
Extended Stay 29
Luxury accommodations 29
Cheap and budget hotels 17
Hotels with indoor pool 12
Business hotels 10
Family Friendly hotels 6
Jacuzzi 5
Golf hotels 4
Private Villas 4
Sustainability certification 4
Exceptional design hotels 3
Historical hotels 3
Central hotels 3
Boutique hotels 3
Spa hotels 2
Self Catering 1
Resorts 1
Casino hotels 1
Romantic hotels 1
Luxury hotels 1
Travel Proud 1
All Saint Charles hotels

Hotels by location

Nearby
City Center Saint Charles 29
Great Skate Roller Rink Saint Charles 6
Swing-A-Round Family Fun Ctr Saint Charles 15
Saint Charles County Community 10
Zumbehl Commons Shopping Center 27
Lindenwood University Saint Charles 34
American Legion Saint Charles 33
Conservatory Saint Charles 31
Grand Prix Karting Saint Charles 6
St Charles Convention Center 32
Cornerstone Salon Professional Saint Charles 29
Ameristar Casino St. Charles 30
Knights of Columbus Saint Charles 29
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Missouri >
Saint Charles

Welcome to Saint Charles

Nestled in the heart of Missouri, Saint Charles offers a charming glimpse into America's history, with cobblestone streets, vintage shops, and taverns that hark back to the days of the wild west. Immerse yourself in local culture by exploring the Lewis and Clark Boathouse and Nature Center, or by taking a stroll along the Missouri River. With an abundance of delectable dining options and stylish boutique hotels, Saint Charles is the perfect destination for a weekend getaway or a longer, more relaxing stay. Come explore this vibrant city for yourself and experience all that Saint Charles has to offer.

What our users say about Saint Charles hotels

Hyatt Regency Saint Louis At The Arch
9.8

Exceptional

us Eugene 27 November 2022
We liked the hotel, ideal for our purposes. The restaurant was just a pleasant stroll away from the property.
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Palace View Resort By Spinnaker
9.8

Exceptional

us Gloria 20 October 2022
The hotel was convenient and fairly clean inside, I loved it. The staff were all amicable, knowledgeable.
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Hilton St. Louis At The Ballpark
9.8

Exceptional

us James 24 February 2023
All the staff is helpful and is engaged to make your stay nice. The location is best possible and ideal, not too far from Night.
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St. Louis Union Station Hotel, Curio Collection By Hilton
9.8

Exceptional

us Thomas 31 December 2022
The staff here are friendly and willing to help at any time. We had a double room with a lovely garden view 🌿 and everything in the room was in good working order.
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Clayton Plaza Hotel & Extended Stay
9.8

Exceptional

us Kathryn 02 April 2023
This place is beautiful, clean, and deserves a rating higher than 4 stars, providing a comfortable and convenient location.
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Angad Arts Hotel St. Louis, Tapestry Collection By Hilton
9.8

Exceptional

us William 30 September 2022
The hotel is unique and clean, with spectacular views of downtown. the room was immaculate and impressive, with a private bathroom, shower, hairdryer, and terry bathrobes. the location is favorable and unbeatable in the St Louis arts district, with easy access to restaurants and the Sheldon theater.
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Branson King Resort & Suites
9.8

Exceptional

us David 18 July 2021
Everything was lovely and spotless, I liked staff and rooms. Nice lobby.
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The Last Hotel
9.4

Excellent

us Leon 28 February 2023
The staff here was friendly and really helped us out. We're already planning our next trip back. It was a great spot to see the sights and we had a blast! 😊
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Hotelumiere At The Arch, A Caesars Destination
9.8

Exceptional

us Edmund 29 March 2022
The hotel was straightforward and the location was cozy near to Busch stadium as well as the river. Light, gorgeous room with a let out couch.
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Grand Crowne Resort
9.8

Exceptional

us Robert 05 July 2022
I loved that the hotel was stunningly beautiful and fairly clean. The room was well stocked, terrific. I had a marvellous view here. I had a very very good stay and would have extended the stay, thank you.
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Save time on your trip arrangements by booking one of our hand-picked hotels

Top 5-star hotels
Exclusive 3-star hotels
Quality 2-star hotels
Indulge yourself with luxury and comfort as you explore the exciting attractions of Saint Charles.
Ameristar Casino Resort And Spa

1 Ameristar Boulevard, Saint Charles, United States

Excellent
81 reviews

253 US$

min. price/night

Enjoy truly authentic experiences without compromising comfort and convenience.
Country Inn & Suites By Radisson, St Charles Historic District

1190 South Main Street, Saint Charles, United States

Excellent
1085 reviews

118 US$

min. price/night

Best Western Plus The Charles Hotel

1425 S 5Th Street, Saint Charles, United States

Good
517 reviews

86 US$

min. price/night

Drury Plaza Hotel St. Louis St. Charles

380 Mulholland Drive, Saint Charles, United States

Excellent
477 reviews

140 US$

min. price/night

Embassy Suites By Hilton Saint Louis Saint Charles

Two Convention Center Plaza, Saint Charles, United States

Excellent
335 reviews

129 US$

min. price/night

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Discover the hidden gems of Saint Charles by booking one of its budget-friendly hotels.
Relax Inn Saint Charles

3800 Harry S. Truman Boulevard, Saint Charles, United States

Good
681 reviews

70 US$

min. price/night

Comfort Suites St Charles-St Louis

1400 South Fifth Street, Saint Charles, United States

Good
471 reviews

146 US$

min. price/night

Woodspring Suites St Louis St Charles

2100 Old Hwy 94 S, Saint Charles, United States

Average
161 reviews

81 US$

min. price/night

Holiday Inn Express Hotel & Suites St. Charles By Ihg

3098 Elm Point Industrial Drive, Saint Charles, United States

Excellent
97 reviews

134 US$

min. price/night

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Travelers’ choice

Check out the most booked accommodations to find reliable places that our users have tried and tested.
Super 8 By Wyndham St Charles Hotel

3040 West Clay, Saint Charles, United States

Good
346 reviews

57 US$

min. price/night

Main Street Balcony Apartment For Up To 8 Guests!

334 N. Main Street Apartment A, Saint Charles, United States

Excellent
15 reviews

269 US$

min. price/night

The Historic Bricks On Main Apartment

213 N. Main Street

Good
13 reviews

160 US$

min. price/night

Main Street Living! 2 Bedroom Unit Right On Main!

703 South Main Street

Good
10 reviews

330 US$

min. price/night

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